For an ISPF session

You can use the standard ISPF capability of assigning functions to PF keys by calling the ISPF command KEYS. Most PF keys in Monitor II have the standard setting as in all other ISPF applications. There are two exceptions:
PF5
RFIND command
PF6
SORT command
If you want to make your own settings, you might use PF10 and PF11 (or PF13 — PF24), they have no predefined meaning in an ISPF Monitor II session. All PF key definitions remain valid across sessions.