Example: Symptomatology of Eating Disorders

Eating disorders are debilitating illnesses associated with disturbances in eating behavior, severe body image distortion, and an obsession with weight that affects the mind and body simultaneously. Millions of people are affected each year, with adolescents particularly at risk. Treatments are available and most are helpful when the condition is identified early.

A health professional can attempt to diagnose an eating disorder through a psychological and medical evaluation. However, it can be difficult to assign a patient to one of several different classes of eating disorders because there is no standardized symptomatology of anorectic/bulimic behavior. Are there symptoms that clearly differentiate patients into the four groups? Which symptoms do they have in common?

In order to try to answer these questions, researchers 1 made a study of 55 adolescents with known eating disorders, as shown in the following table.

Table 1. Patient diagnoses
Diagnosis Number of Patients
Anorexia nervosa 25
Anorexia with bulimia nervosa 9
Bulimia nervosa after anorexia 14
Atypical eating disorder 7
Total 55

Each patient was seen four times over four years, for a total of 220 observations. At each observation, the patients were scored for each of the 16 symptoms outlined in the following table. Symptom scores are missing for patient 71 at time 2, patient 76 at time 2, and patient 47 at time 3, leaving 217 valid observations. The data can be found in anorectic.sav.See the topic Sample Files for more information.

Table 2. Modified Morgan-Russell subscales measuring well-being
Variable name Variable label Lower end (score1) Upper end (score 3 or 4)
weight Body weight Outside normal range Normal
mens Menstruation Amenorrhea Regular periods
fast Restriction of food intake (fasting) Less than 1200 calories Normal/regular meals
binge Binge eating Greater than once a week No bingeing
vomit Vomiting Greater than once a week No vomiting
purge Purging Greater than once a week No purging
hyper Hyperactivity Not able to be at rest No hyperactivity
fami Family relations Poor Good
eman Emancipation from family Very dependent Adequate
frie Friends No good friends Two or more good friends
school School/employment record Stopped school/work Moderate to good record
satt Sexual attitude Inadequate Adequate
sbeh Sexual behavior Inadequate Can enjoy sex
mood Mental state (mood) Very depressed Normal
preo Preoccupation with food and weight Complete No preoccupation
body Body perception Disturbed Normal

Principal components analysis is ideal for this situation, since the purpose of the study is to ascertain the relationships between symptoms and the different classes of eating disorders. Moreover, categorical principal components analysis is likely to be more useful than classical principal components analysis because the symptoms are scored on an ordinal scale.

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1 Van der Ham, T., J. J. Meulman, D. C. Van Strien, and H. Van Engeland. 1997. Empirically based subgrouping of eating disorders in adolescents: A longitudinal perspective. British Journal of Psychiatry, 170, 363-368.