I'm currently working on a project that is deploying a portal (LifeRay), Quickr 8.2, Connections 2.5, Sametime 8.5, iNotes 8.5 as the main components. My part is the install and integration of Sametime. The install consists of a pre-production environment, and a production environment spread over two geographies: Europe and Asia Pacific.
The pre-production environment has a ST Community server, a ST Proxy server, a ST Media Manager server, and a ST Gateway server. The ST Meeting server is not required.
In the production environment, for each geography (Europe and Asia Pacific), there is a cluster of 2 ST Community servers, a cluster of 2 ST Proxy servers, a ST Media Manager, and a ST Gateway.
The ST System Console that will manage the servers is installed in Europe.
The challenges we've seen so far have been related to the network. I will write up a separate post once we have some networking issues worked out.