Are you using the Debug Tool - DT/VSE ?
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The Debug Tool for VSE/ESA (DT/VSE) provides advanced facilities for debugging and testing applications compiled with the following IBM high-level compilers:
It helps examine, monitor, and control the execution of application programs by enabling:
DT/VSE just releases an APAR, that is required for CICS TS for z/VSE 2.1. It's the first product that adapted to our new CICS version to be released in 4Q2015 together with z/VSE 6.1.
APAR PI28537 (PTF UI28417): USE DT/VSE WITH CICS TS FOR Z/VSE
Description: The PTF for this APAR is required to run DT/VSE ON CICS/TS for z/VSE 2.1.0.