Jazz architecture: Planning for multiple application server instances
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The Jazz architecture allows for multiple instances of specific application servers, such as the Change and Configuration Management (CCM) application (Rational Team Concert), Quality Management (QM) application (Rational Quality Manager) and Requirements Management (RM) application (DOORS Next Gen). These application servers are registered to a common Jazz Team Server (JTS) to form a CLM Instance. The architecture further allows multiple CLM Instances to be formed. You should be aware of the tradeoffs and architectural considerations when multiple instances are needed in order to scale to support your user population/load.
The following article on jazz.net provides details about application, server and architectural considerations in addition to functional differences that you should review while planning: Planning for multiple Jazz application server instances