This week's issue of the Economist has a couple of interesting articles regarding the most recent grant from the Bill and Melinda Gates Foundation, some $750 million for the Global Alliance for Vaccines and Immunisation. The article goes on to suggest that "biology is basically a software problem in which biochemical pathways stand in for computer algorithms." A bit naive of a comparison, although increasingly it appears that one limiting factor in genomic research is the ability to develop the right software.
On a FAR more mundane subject, I'm toiling away this evening on the Handbook's architecture metamodel. I've been classifying the three foot pile of notes I've collected on various systems, and have realized that there were some gaps and overlaps in instantiating the earlier version of the metamodel. As I mentioned, I've been using the Rose Software Architect, which lives inside Ecilpse; it's really very sweet! If you happen to look at the metamodel section while I'm still in progress, you'll find some new models and some old Rational Rose models - the contrast in the visualizations reminds me of the gulf between the first Macintosh operating system and the current OS X.