Recently, IBM and the University of Texas Medical Branch (UTMB) [launched an effort] using IBM's World Community Grid "virtual supercomputer" to allow laboratory tests on drug candidates for drug-resistant influenza strains and new strains, such as H1N1 (aka "swineflu"), in less than a month.
Researchers at the University of Texas Medical Branch will use [World Community Grid] to identify the chemical compounds most likely to stop the spread of the influenza viruses and begin testing these under laboratory conditions. The computational work adds up to thousands of years of computer time which will be compressed into just months using World Community Grid. As many as 10 percent of the drug candidates identified by calculations on World Community Grid are likely to show antiviral activity in the laboratory and move to further testing.
According to the researchers, without access to World Community Grid's virtual super computing power, the search for drug candidates would take a prohibitive amount of time and laboratory testing.
A few months after Larry's "call to action" in 2006, IBM and over twenty major worldwide public health institutions, including the World Health Organization [WHO] and the Centers for Disease Control and Prevention [CDC], [announced the Global Pandemic Initiative], a collaborative effort to help stem the spread of infectious diseases.
One might think that with our proximity to Mexico that the first cases would have been the border states, such as Arizona, but instead there were cases as far away as New York and Florida. The NYT explains in an article [Predicting Flu With the Aid of (George) Washington] that two rival universities, Northwestern University and Indiana University, both predicted that there would be about 2500 cases in the United States, based on air traffic control flight patterns, and the tracking data from a Web site called ["Where's George"] which tracks the movement of US dollar bills stamped with the Web site URL.
The estimates were fairly close. According to the Centers for Disease Control and Prevention [H1N1 Flu virus tracking page], there are currently 3009 cases of H1N1 in 45 states, as of this writing.
This is just another example on how an information infrastructure, used properly to provide insight, make predictions, and analyze potential cures, can help the world be a smarter planet. Fortunately, IBM is leading the way.Read More]
Comments (4) Visits (7138)
My post last week [Solid State Disk on DS8000 Disk Systems] kicked up some dust in the comment section.Fellow blogger BarryB (a member of the elite [Anti-Social Media gang from EMC]) tried to imply that 200GB solid state disk (SSD) drives were different or better than the 146GB drives used in IBM System Storage DS8000 disk systems. I pointed out that they are the actual same physical drive, just formatted differently.
To explain the difference, I will first have to go back to regular spinning Hard Disk Drives (HDD). There are variances in manufacturing, so how do you make sure that a spinning disk has AT LEAST the amount of space you are selling it as? The solution is to include extra. This is the same way that rice, flour, and a variety of other commodities are sold. Legally, if it says you are buying a pound or kilo of flour, then it must be AT LEAST that much to be legal labeling. Including some extra is a safe way to comply with the law. In the case of disk capacity, having some spare capacity and the means to use it follows the same general concept.
(Disk capacity is measured in multiples of 1000, in this case a Gigabyte (GB) = 1,000,000,000 bytes, not to be confused with [Gibibyte (GiB)] = 1,073,741,824 bytes, based on multiples of 1024.)
Let's say a manufacturer plans to sell 146GB HDD. We know that in some cases there might be bad sectors on the disk that won't accept written data on day 1, and there are other marginally-bad sectors that might fail to accept written data a few years later, after wear and tear. A manufacturer might design a 156GB drive with 10GB of spare capacity and format this with a defective-sector table that redirects reads/writes of known bad sectors to good ones. When a bad sector is discovered, it is added to the table, and a new sector is assigned out of the spare capacity.Over time, the amount of space that a drive can store diminishes year after year, and once it drops below its rated capacity, it fails to meet its legal requirements. Based on averages of manufacturing runs and material variances, these could then be sold as 146GB drives, with a life expectancy of 3-5 years.
With Solid State Disk, the technology requires a lot of tricks and techniques to stay above the rated capacity. For example, you can format a 256GB drive as a conservative 146GB usable, with an additional 110GB (75 percent) spare capacity to handle all of the wear-leveling. You could lose up to 22GB of cells per year, and still have the rated capacity for the full five-year life expectancy.
Alternatively, you could take a more aggressive format, say 200GB usable, with only 56GB (28 percent) of spare capacity. If you lost 22GB of cells per year, then sometime during the third year, hopefully under warranty, your vendor could replace the drive with a fresh new one, and it should last the rest of the five year time frame. The failed drive, having 190GB or so usable capacity, could then be re-issued legally as a refurbished 146GB drive to someone else.
The wear and tear on SSD happens mostly during erase-write cycles, so for read-intensive workloads, such as boot disks for operating system images, the aggressive 200GB format might be fine, and might last the full five years.For traditional business applications (70 percent read, 30 percent write) or more write-intensive workloads, IBM feels the more conservative 146GB format is a safer bet.
This should be of no surprise to anyone. When it comes to the safety, security and integrity of our client's data, IBM has always emphasized the conservative approach.[Read More]
Comments (6) Visits (8570)
Looks like fellow blogger and arch nemesis BarryB from EMC is once again stirring up trouble, this time he focuses his attention on IBM's leadership in Solid State Disk (SSD) on the IBM System Storage DS8000 disk systems in his post [IBM's amazing splash dance, part deux], a follow-up to [IBM's amazing splash dance] and multi-vendor tirade [don't miss the amazing vendor flash dance].
(Note: IBM [Guidelines] prevent me from picking blogfights, so this post is only to set the record straight on some misunderstandings, point to some positive press about IBM's leadership in this area, and for me to provide a different point of view.)
First, let's set the record straight on a few things. The [RedPaper is still in draft form] under review, and so some information has not yet been updated to reflect the current situation.
I find it amusing that BarryB's basic argument is that IBM's initial release of SSD disk on DS8000 is less than what the potential architecture could be extended to support much more. Actually, if you look at EMC's November release of Atmos, as well as their most recent announcement of V-Max, they basically say the same thing "Stay Tuned, this is just our initial release, with various restrictions and limitations, but more will follow." Architecturally, IBM DS8000 could support a mix of SSD and non-SSD on the same DA pairs, could support RAID6 and RAID10 as well, and could support larger capacity drives or use higher-capacity read-intensive formats. These could all be done via RPQ if needed, or in a follow-on release.
BarryB's second argument is that IBM is somehow "throwing cold water" on SSD technology. That somehow IBM is trying to discourage people from using SSD by offering disk systems with this technology. IBM offered SSD storage on BladeCenter servers LONG BEFORE any EMC disk system offering, and IBM continues to innovate in ways that allow the best business value of this new technology. Take for example this 24-page IBM Technical Brief:[IBM System z® and System Storage DS8000:Accelerating the SAP® Deposits Management Workload With Solid State Drives]. It is full of example configurations that show that SSD on IBM DS8000 can help in practical business applications. IBM takes a solution view, and worked with DB2, DFSMS, z/OS, High Performance FICON (zHPF), and down the stack to optimize performance to provide real business value innovation. Thanks to this synergy,IBM can provide 90 percent of the performance improvement with only 10 percent of the SSD disk capacity as EMC offerings. Now that's innovative!
The price and performance differences between FC and SATA (what EMC was mostly used to) is only 30-50 percent. But the price and performance differences between SSD and HDD is more than an order of magnitude in some cases 10-30x, similar to the differences between HDD and tape. Of course, if you want hybrid solutions that take best advantage of SSD+HDD, it makes more sense to go to IBM, the leading storage vendor that has been doing HDD+Tape hybrid solutions for the past 30 years. IBM understands this better, and has more experience dealing with these orders of magnitude than EMC.
But don't just take my word for it. Here is an excerpt from Jim Handy, from [Objective Analysis] market research firm, in a recent Weekly Review from [Pund-IT] (Volume 5, Issue 23--May 6, 2009):
As for why STEC put out a press release on their own this week without a corresponding IBM press release, I can only say that IBM already announced all of this support back in February, and I blogged about it in my post [Dynamic Infrastructure - Disk Announcements 1Q09]. This is not the first time one of IBM's suppliers has tried to drum up business in this manner. Intel often funds promotions for IBM System x servers (the leading Intel-based servers in the industry) to help drive more business for their Xeon processor.
So, BarryB, perhaps its time for you to take out your green pen and work up another one of your all-too-common retraction and corrections.[Read More]
Wrapping up this week's theme on Cloud Computing, I finish with an IBM announcement for two new products to help clients build private cloud environments from their existing Service Oriented Architecture (SOA) deployments.
With more than 7,000 customer implementations worldwide, IBM is the SOA market leader. Of course, both of these products above can be used with IBM System Storage solutions, including Cloud-Optimized Storage offerings like Grid Medical Archive Solution (GMAS), Grid Access Manager software, Scale-Out File Services (SoFS), and the IBM XIV disk system.
IBM is part of the "Cloud Computing 5" major vendors pushing the envelope (the other four are Google, Microsoft, Amazon and Yahoo). In fact, IBM has a number of initiatives that allow customers to leverage IBM software in a cloud. IBM is working in collaboration with Amazon Web Services (AWS), a subsidiary of Amazon.com, Inc. to make IBM software available in the Amazon Elastic Compute Cloud (Amazon EC2). WebSphere sMash, Informix Dynamic Server, DB2, and WebSphere Portal with Lotus Web Content Management Standard Edition are available today through a "pay as you go" model for both development and production instances. In addition to those products, IBM is also announcing the availability of IBM Mashup Center and Lotus Forms Turbo for development and test use in Amazon EC2, and intends to add WebSphere Application Server and WebSphere eXtreme Scale to these offerings.
For more about IBM's leadership in Cloud Computing, see the IBM [Press Release].Read More]