When backing up databases using the VSS backup method, you can improve the backup performance by telling FlashCopy Manager to use multiple sessions to communicate with the TSM Server. (This tip assumes you are using multiple disks or LUNs for your database, for example, separate LUNs for your data files and your log files). To do this, set the RESOURCEUTLIZATION parameter in the backup-archive client dsm.opt file. The TSM Performance Tuning Guide (PDF) suggests a value of 5 or 10.
Secondly, when backing up Microsoft Exchange databases, it may be possible to improve performance by skipping the integrity check of the databases. Typically, Microsoft requires an integrity check before a backup is considered "good." However, in Exchange 2010 Database Availability Group (DAG) environments, Microsoft states: "For databases in a DAG that has two or more healthy copies, the database consistency checking step can even be skipped." You should evaluate whether skipping the integrity check is appropriate for your environment. If so, you can tell FlashCopy Manager to skip the integrity check with the SKIPINTEGRITYCHECK parameter.