Do you know setting incorrect locale for TXSeries leads to unexpected issues?
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All locale specific environment variables (LANG, LC_*, etc.) in the system need to be set to any one of the TXSeries supported locale value only. Otherwise, you might see unexpected CICS behavior and issues. For example, you might see an issue like CICS Application Server(CICSAS) processes getting terminated with SIGSEGV.
You can find the TXSeries supported locales at Installing section under Planning your installation guide at TXSeries Knowledge Center.